Posted by: Indonesian Children | April 15, 2010

Bronchopulmonary manifestations of gastroesophageal reflux disease

Internist (Berl). 2010 Mar;51 Suppl 1:246-54.

Bronchopulmonary manifestations of gastroesophageal reflux disease

[Article in German]

Malfertheiner MV, Kandulski A, Malfertheiner P, Schreiber J.

Fachbereich für Pneumologie, Otto-von-Guericke-Universität Magdeburg, Leipziger Strasse 44, 39120, Magdeburg, Deutschland.


Gastroesophageal reflux disease (GERD) is a common disease in the western world. Usually it occurs with typical symptoms like heartburn and regurgitation, but almost every third GERD-patient presents with extraesophageal symptoms and diseases in which a causal relation with GERD is discussed. The extraesophageal symptoms possibly associated with GERD are chronic cough, bronchial asthma, sleep disturbances including obstructive sleep apnea, hoarseness, dental erosions, non-cardiac chest pain and idiopathic pulmonary fibrosis. This article gives an overview of the reflux-associated diseases of the airways as well as the proposed pathomechanisms and therapeutic options.

PMID: 20098976 [PubMed – in process]

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