Posted by: Indonesian Children | April 15, 2010

The role of inflammation and allergy in acute coronary syndromes.

Inflamm Allergy Drug Targets. 2008 Sep;7(3):136-44.

The role of inflammation and allergy in acute coronary syndromes.

Ozben B, Erdogan O.

Department of Cardiology, Marmara University School of Medicine, Istanbul, Turkey. besteozben@yahoo.com

Abstract

It is well known that inflammatory mechanisms play a crucial role in the pathogenesis of atherosclerosis and coronary artery disease. In recent years, allergic episodes have been shown to be associated with acute coronary syndromes. Mast cells release certain inflammatory mediators including histamine and neutral proteases during an allergic episode and these inflammatory mediators are implied to induce coronary artery spasm and/or atheromatous plaque erosion or rupture. As the inflammatory component of acute coronary syndromes is a potential therapeutic target, drugs that stabilize mast cell membrane and monoclonal antibodies that protect mast cell surface may be effective in preventing allergy associated acute coronary syndromes. In this review, we will mention the role of inflammation and allergy and anti-inflammatory therapeutic modalities in acute coronary syndromes.

PMID: 18782020 [PubMed – indexed for MEDLINE]

 

Provided by

children’s ALLERGY CENTER online

JL TAMAN BENDUNGAN ASAHAN 5 JAKARTA PUSAT, JAKARTA INDONESIA 10210

PHONE : (021) 70081995 – 5703646

email :  judarwanto@gmail.com\ 

htpp://www.childrenallergyclinic.wordpress.com/ 

 

 

 

Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. You should carefully read all product packaging. If you have or suspect you have a medical problem, promptly contact your professional healthcare provider. 

Copyright © 2010, Children Allergy Center Information Education Network. All rights reserved


Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

Categories

%d bloggers like this: